古塞奇尤单抗/戈利木单抗（JNJ-78934804）注射液III期临床试验-一项在中重度活动性溃疡性结肠炎受试者中评估JNJ-78934804的研究（DUET ENCORE-UC）

登记号	CTR20262546	试验状态	进行中
申请人联系人	李晓讴	首次公示信息日期	2026-07-02
申请人名称	Janssen Research & Development, LLC/ 强生（中国）投资有限公司/ Cilag AG

登记号	CTR20262546
相关登记号	暂无
药物名称	古塞奇尤单抗/戈利木单抗（JNJ-78934804）注射液
药物类型	生物制品
临床申请受理号	企业选择不公示
适应症	溃疡性结肠炎
试验专业题目	一项在中重度活动性溃疡性结肠炎试验参与者中评价JNJ-78934804疗效和安全性的III期、随机、双盲、阳性对照、多中心研究
试验通俗题目	一项在中重度活动性溃疡性结肠炎受试者中评估JNJ-78934804的研究（DUET ENCORE-UC）
试验方案编号	78934804UCO3001	方案最新版本号	原始版本
版本日期:	2026-03-07	方案是否为联合用药	否

申请人名称	[["Janssen Research & Development, LLC"],["强生（中国）投资有限公司"],["Cilag AG"]]
联系人姓名	李晓讴	联系人座机	010-59524708	联系人手机号
联系人Email	xli188@its.jnj.com	联系人邮政地址	北京市-北京市-朝阳区建国路77号华贸中心写字楼3号楼19层	联系人邮编	100025

本研究旨在评价JNJ-4804在第48周相较于古塞奇尤单抗的疗效

试验分类	安全性和有效性	试验分期	III期	设计类型	平行分组
随机化	随机化	盲法	双盲	试验范围	国际多中心试验

年龄	18岁(最小年龄)至 无上限 (最大年龄)
性别	男+女
健康受试者	无
入选标准	[["签署知情同意时年龄≥18岁"],["筛选前至少12周已确诊溃疡性结肠炎（UC）"],["根据改良Mayo评分评估为中重度活动性UC"],["筛选期内镜中心阅片内镜评分≥2"],["研究药物首次给药前患有UC广泛性病变≥8年或病变局限于左半结肠≥10年的试验参与者必须在研究药物首次给药前1年内接受过全结肠镜检查以评估异型增生"],["不符合异型增生筛查标准要求且≥45岁的试验参与者必须在研究药物首次给药前5年内接受过完整的结肠镜检查，评估是否存在腺瘤性息肉"],["对既往已获批的系统性治疗（ST）存在初始应答不足、失应答或不耐受"],["符合方案规定的UC合并用药要求"],["如果接受胰高血糖素样肽-1激动剂，必须已接受GLP-1激动剂≥20周，并在第0周前接受稳定剂量治疗≥4周；如果近期停用，必须已停用≥4周或5个半衰期（以较长者为准）"],["筛选期实验室检查符合方案规定范围"],["符合方案规定的性行为及避孕药/屏障避孕要求"],["必须提供知情同意书"],["如果试验参与者同意参加可选肠道超声子研究，则必须签署单独的知情同意书（ICF）。拒绝签署可选IUS子研究的知情同意书不会导致试验参与者被排除出主研究"],["试验参与者应愿意并能够遵循本研究方案规定的所有要求，包括但不限于完成评估、遵循访视计划和依从生活方式限制项目"]]
排除标准	[["符合方案定义的重度广泛性结肠炎"],["存在造瘘口"],["筛选期内镜检查视频结果表明患有孤立性直肠炎"],["存在瘘管或有瘘管病史"],["筛选前10周内接受过手术或计划在研究期间接受可能混淆研究药物获益评价的手术，或者存在其他可能混淆研究药物治疗获益评价的状况"],["存在症状性结肠或小肠梗阻，通过客观影像学检查或内镜检查证实有狭窄并导致梗阻"],["有广泛性结肠切除史（即剩余结肠＜30 cm）或因接受结肠切除术导致疾病严重程度评估方法（例如Mayo评分）对研究药物应答情况的评估过程受到不利影响"],["已知结肠炎（活动性或既往）区域结肠黏膜异型增生病史，或筛选期结肠镜检查发现高度或低度结肠黏膜异型增生。病理学结果为不确定性异型增生伴反应性不典型增生时，不排除试验参与者"],["筛选期内镜检查可见腺瘤性结肠息肉且在基线（第0周）前未切除，或既往有未切除的腺瘤性结肠息肉病史"],["诊断为未定型结肠炎、显微镜下结肠炎、缺血性结肠炎或克罗恩结肠炎，或存在任何提示克罗恩病（CD）的检查结果"],["研究药物首次给药前16周内肠道病原体（包括艰难梭菌[旧称为难辨梭菌]毒素）粪便培养或其他检查结果为阳性，重复检查结果为阴性且无该病原体持续感染症状的试验参与者除外"],["有活动性结核（TB）病史，或在筛选时存在提示活动性结核的症状或体征，在筛选前有未经治疗的潜伏性结核病史。已在筛选前完成潜伏性结核治疗的受试者可纳入"],["存在潜伏性或活动性肉芽肿感染病史"],["曾患或现患慢性或复发性感染性疾病"],["曾患或现患非结核性分枝杆菌感染或具有临床意义的机会感染"],["研究药物首次给药前8周内出现具有临床意义的感染体征和症状，因感染住院，或因感染接受胃肠外抗生素治疗"],["有证据表明在研究药物首次给药前8周内发生过带状疱疹感染"],["研究药物首次给药前≤4周新型冠状病毒感染检测呈阳性或有COVID-19暴露史"],["基线前6周内存在以下任一情况（不考虑疫苗接种状态）：na.t确诊M痘感染（检测阳性），或nb.t疑似M痘感染（有M痘的临床特征，但没有相应检测结果记录），或nc.t与已知或疑似M痘感染者密切接触"],["当前患有恶性肿瘤或筛选前5年内有恶性肿瘤史（接受过充分治疗且研究药物首次给药前≥12个月无复发证据的非黑色素瘤皮肤癌，以及接受过治疗且研究药物首次给药前≥12个月无复发证据的宫颈原位癌除外）"],["已知有淋巴细胞增生性疾病史，包括淋巴瘤、白血病和多发性骨髓瘤；有意义不明的单克隆丙种球蛋白病史；或提示可能存在淋巴细胞增生性疾病的体征和症状，如淋巴结病或脾肿大"],["有脱髓鞘类疾病史，如多发性硬化或视神经炎"],["曾患或现患有充血性心脏衰竭（CHF）（包括已用药物控制的无症状CHF）"],["有严重、进行性或未控制的肾脏、泌尿生殖系统、肝脏、胆道、血液系统、内分泌系统、心脏、血管、肺部、风湿病、神经系统、精神疾病或代谢紊乱病史，或存在相关体征和症状"],["诊断为PSC且在基线前符合方案规定的至少一项肝功能标准，或影像学检查显示存在主导性狭窄"],["接受过实质或淋巴器官移植（筛选前＞12周接受过角膜移植除外）"],["筛选前1年内有符合《精神障碍诊断和统计手册》（第5版文本修订版，DSM-5-TR）标准的药物或酒精滥用史；使用大麻不一定导致试验参与者被排除（如果当地法规允许），除非研究者认定为滥用"],["既往有提示狼疮样综合征的症状"],["已知对古塞奇尤单抗或其任何辅料、戈利木单抗或其任何辅料或JNJ-4804或其任何辅料过敏、有超敏反应或不耐受"],["经研究者或申办方判定，既往使用古塞奇尤单抗单药或戈利木单抗单药治疗UC时存在初始应答不足或失应答"],["在第0周前规定的洗脱期内，接受过任何药物或治疗（皮质类固醇、环孢霉素、他克莫司、西罗莫司或吗替麦考酚酯"],["在筛选期间启用任何系统性治疗"],["基线前≤12个月接种过卡介苗或在基线前≤12周接种过任何其他活疫苗，或计划在研究期间和研究药物末次给药后16周内接种任何活疫苗"],["入组本研究时或在研究药物末次给药后6个月内怀孕、哺乳或计划怀孕的女性试验参与者"],["入组本研究时或在研究药物末次给药后6个月内有生育计划的男性试验参与者"],["目前正在参加或计划在本研究开展期间参加另一项使用试验用药物、器械或程序的研究"],["胸部X线检查结果异常，提示存在未确诊的有临床意义肺部病变，包括但不限于恶性肿瘤、既往未识别的肺部病变，以及TB、组织胞浆菌病或球孢子菌病引起的活动性或潜伏性感染"],["有人类免疫缺陷病毒（HIV）抗体阳性史，或筛选时HIV检测结果呈阳性"],["丙型肝炎病毒抗体检测结果阳性"],["乙型肝炎病毒感染检测结果呈阳性"],["研究者或研究中心的雇员，能直接参与该研究者或研究中心负责的拟定研究或其他研究，以及这类雇员或研究者的家属"],["对静脉穿刺耐受性差，或在研究期间缺乏足够的静脉通路用于采集所需的血液样本"],["弱势人群（例如，受保护或被剥夺自由的成年人、无法表示同意的成年人）、研究者或研究中心的雇员（直接参与本研究，或参与本研究的研究者或研究中心负责的其他研究），以及这些雇员或研究者的家属"],["存在研究者或申办方认为参加本研究并不符合试验参与者最佳利益（例如，损害健康）或可能妨碍、限制或干扰方案规定评估的情况"]]

试验药

[["中文通用名:JNJ-78934804(JNJ-4804) 英文通用名:JNJ-78934804(JNJ-4804) 商品名称:NA","剂型:注射剂 规格:不适用 用法用量:受试者在第0、4和8周接受JNJ-78934804皮下注射诱导剂量，第12周开始每4周一次接受JNJ-78934804皮下注射维持剂量。符合补救治疗标准则在第16、20和24周接受JNJ-78934804诱导剂量，第28周开始维持给药。长期扩展期中继续第44周给药方案，且在第48周首次给药 用药时程:受试者在第0、4和8周接受JNJ-78934804诱导剂量，第12周至44周每4周一次接受JNJ-78934804维持剂量。符合补救治疗标准则在第16、20和24周接受JNJ-78934804诱导剂量，第28周至140周开始维持给药。长期扩展期中第48周至140周接受JNJ-78934804治疗"]] 序号 名称 用法

对照药

[["中文通用名:古塞奇尤单抗 英文通用名:Guselkumab 商品名称:特诺雅","剂型:注射剂 规格:不适用 用法用量:受试者在第0、4和8周接受古塞奇尤单抗皮下注射诱导剂量，第12周开始每4周一次接受古塞奇尤单抗皮下注射维持剂量。符合补救治疗标准则在第16、20和24周接受JNJ-78934804诱导剂量，第28周开始维持给药。长期扩展期中继续第44周给药方案，且在第48周首次给药 用药时程:受试者在第0、4和8周接受古塞奇尤单抗诱导剂量，第12周至44周每4周一次接受古塞奇尤单抗维持剂量。符合补救治疗标准则在第16、20和24周接受JNJ-78934804诱导剂量，第28周至140周开始维持给药。长期扩展期中第48周至140周接受JNJ-78934804治疗"]] 序号 名称 用法

主要终点指标及评价时间

[["第48周时临床缓解的受试者比例","第48周","有效性指标"]] 序号 指标 评价时间 终点指标选择

次要终点指标及评价时间

[["第48周时内镜改善的受试者比例","第48周","有效性指标"],["第48周时90天无皮质类固醇临床缓解的受试者比例","第48周","有效性指标"],["第48周时组织学缓解与内镜改善复合终点的受试者比例","第48周","有效性指标"],["第48周时疲劳应答（患者报告结局测量信息系统[PROMIS]疲劳简表7a）的受试者比例","第48周","有效性指标"],["维持Mayo排便次数（SF）评分≤1分且便血（RB）评分＝0分的受试者比例n第12、24和48周这三个评估时间点报告SF评分为0或1且RB评分为0的受试者所占比例","第12、24、48周","有效性指标"],["第48周时腹痛缓解的受试者比例","第48周","有效性指标"],["第12周时临床缓解的受试者比例","第12周","有效性指标"],["第12周时内镜改善的受试者比例","第12周","有效性指标"],["第2周时Mayo SF/RB应答的受试者比例","第2周","有效性指标"],["不良事件（AE）和严重不良事件（SAE）的发生率和类型","最长至约3年","安全性指标"]] 序号 指标 评价时间 终点指标选择

1	姓名	陈旻湖	学位	医学博士	职称	主任医师
	电话	020-87330631	Email	chenminhu@vip.163.com	邮政地址	广东省-广州市-越秀区中山二路58号
	邮编	510080	单位名称	中山大学附属第一医院

[["中山大学附属第一医院","陈白莉","中国","广东省","广州市"],["中日友好医院","王晓娣","中国","北京市","北京市"],["安徽医科大学第一附属医院","胡乃中","中国","安徽省","合肥市"],["浙江大学医学院附属邵逸夫医院","叶玲娜","中国","浙江省","杭州市"],["四川大学华西医院（四川省国际医院）","张虎","中国","四川省","成都市"],["金华市中心医院","丁进","中国","浙江省","金华市"],["中山大学附属第六医院","高翔","中国","广东省","广州市"],["广州医科大学附属第二医院","杨辉","中国","广东省","广州市"],["郑州大学第二附属医院","冯百岁","中国","河南省","郑州市"],["福建医科大学附属第一医院","陈金通","中国","福建省","福州市"],["核工业总医院（苏州大学附属第二医院）","唐文","中国","江苏省","苏州市"],["上海交通大学瑞金医院","邹多武","中国","上海市","上海市"],["吉林大学第一医院","徐红","中国","吉林省","长春市"],["兰州大学第二医院","王祥","中国","甘肃省","兰州市"],["河南科技大学第一附属医院","田笑笑","中国","河南省","洛阳市"],["北京大学第三医院","丁士刚","中国","北京市","北京市"],["南京医科大学附属淮安第一医院","王宏刚","中国","江苏省","淮安市"],["株洲市中心医院","周红兵","中国","湖南省","株洲市"],["佛山第一人民医院","李兆滔","中国","广东省","佛山市"],["重庆市人民医院","郭红","中国","重庆市","重庆市"],["中国医科大学盛京医院","桑力轩","中国","辽宁省","沈阳市"],["常州二院","刘文佳","中国","江苏省","常州市"],["河北医科大学第二医院","张晓岚","中国","河北省","石家庄市"],["北京友谊医院","宗晔","中国","北京市","北京市"],["遵义医科大学附属医院","刘模荣","中国","贵州省","遵义市"],["宁波市医疗中心李惠利医院","周颖","中国","浙江省","宁波市"],["厦门大学附属中山医院","范燕云","中国","福建省","厦门市"],["中国医学科学院北京协和医院","杨红","中国","北京市","北京市"],["十堰市太和医院","金曙","中国","湖北省","十堰市"],["青岛大学附属医院","丁雪丽","中国","山东省","青岛市"],["National Taiwan University Hospital","Shu-Chen Wei","中国台湾","台湾","Taipei"],["Linkou Chang Gung Memorial Hospital","Cheng-Tang Chiu","中国台湾","台湾","Taoyuan"],["Taichung Veterans General Hospital","Chung-Hsin Chang","中国台湾","台湾","Taichung"],["Mackay Memorial Hospital","Horng-Yuan Wang","中国台湾","台湾","Taipei"],["National Cheng Kung University Hospital","Chiao Hsiung Chuang","中国台湾","台湾","Tainan"],["Hospital Provincial del Centenario","Maria Jimena Ortiz","阿根廷","Santa Fe","Rosario"],["GEDYT","Silvina Goncalves","阿根廷","Buenos Aires","Azcuénaga"],["HIGEA","Martin Toro","阿根廷","Mendoza","Mendoza"],["Instituto de Investigaciones Clinicas Quilmes","Paola Andrea Adami","阿根廷","Buenos Aires","Quilmes"],["MR Medicina Reumatologica","Alejandra Cusa","阿根廷","Buenos Aires","San Fernando de la Buena Vista"],["Instituto Medico De Alta Complejidad San Isidro Sa","Maria Alicia Lazaro","阿根廷","Buenos Aires","San Isidro"],["Globalpsy","Julio De Maria","阿根廷","Provincia de Buenos Aires","La Plata"],["Mater Hospital Brisbane","Jakob Begun","澳大利亚","Queensland","South Brisbane"],["Fiona Stanley Hospital","Lena Thin","澳大利亚","Western Australia","Murdoch"],["Monash Medical Centre","Manjeet Sandhu","澳大利亚","Victoria","Clayton"],["The Alfred Hospital","Miles Sparrow","澳大利亚","Victoria","Melbourne"],["Royal Prince Alfred Hospital","Crispin Corte","澳大利亚","New South Wales","Camperdown"],["Macquarie University Hospital","Rupert Leong","澳大利亚","New South Wales","Macquarie Park"],["John Hunter Hospital","Tom Goodsall","澳大利亚","New South Wales","New Lambton Heights"],["Banksia Trials SA","Robert Bryant","澳大利亚","South Australia","Adelaide"],["Knox Private Hospital","Abhinav Vasudevan","澳大利亚","Victoria","Melbourne"],["Melbourne Gut Clinic, Epworth Hospital","Britt Christensen","澳大利亚","Victoria","East Melbourne"],["SA Gastrointestinal Services","Peter Bampton","澳大利亚","South Australia","Kurralta Park"],["Universitaetsklinikum Salzburg - Landeskrankenhaus","Sonja Heeren","奥地利","Salzburg","Salzburg"],["LKH-Univ. Klinikum Graz","Andreas Blesl","奥地利","Styria","Graz"],["Krankenhaus der Barmherzigen Brüder","Alexander Eser","奥地利","Vienna","Vienna"],["Klinikum Klagenfurt am Woerthersee","Markus Peck-Radosavljevic","奥地利","Carinthia","Klagenfurt"],["Allg. Krankenhaus der Landeshauptstadt St. Poelten","Andreas Maieron","奥地利","Lower Austria","Sankt Polten"],["Klinikum Wels-Grieskirchen","Harald Hofer","奥地利","Upper Austria","Wels"],["Kepler Universitatsklinikum (Kepler University Hospital)","Alexander Moschen","奥地利","Upper Austria","Linz"],["UZ Gent","Triana Lobaton Ortega","比利时","Flanders","Gent"],["Universitair Ziekenhuis Brussel Campus Jette","Brecht Hens","比利时","Brussels-Capital Region","Brussels"],["UZ Leuven","Bram Verstockt","比利时","Flanders","Leuven"],["Cliniques Universitaires Saint Luc","Olivier Dewit","比利时","Brussels-Capital Region","Woluwe-Saint-Lambert"],["AZ Sint-Lucas","Julie Busschaert","比利时","Flanders","Bruges"],["AZ Maria Middelares","Didier Baert","比利时","Flanders","Gent"],["HOPITAL ERASME","Denis Franchimont","比利时","Brussels-Capital Region","Anderlecht"],["Imelda Ziekenhuis","Lieven Pouillon","比利时","Flanders","Bonheiden"],["CHC MontLégia","Arnaud Colard","比利时","Waals Gewest","Luik"],["CDC - Centro Digestivo de Curitiba","Odery Ramos Junior","巴西","Paraná","Curitiba"],["BR Trials","Roberto Silva Junior","巴西","Sao Paulo","Sao Paulo"],["Fundacao para o Desenvolvimento Medico Hospitalar (UNESP Botucatu)","Ligia Yukie Sassaki","巴西","Sao Paulo","Botucatu"],["Hospital das Clinicas de Porto Alegre","Luciana Harlacher","巴西","Rio Grande do Sul","Porto Alegre"],["Pesquisare Saude","Alexander de Sa Rolim","巴西","Sao Paulo","Santo André"],["Centro de Estudos Clínicos do Interior Paulista - CECIP","Bruna Meyer De Mattos Correa","巴西","Sao Paulo","Jaú"],["INTEGRAL Pesquisa e Ensino","Herlon Escorsi Valerio","巴西","Sao Paulo","Votuporanga"],["Instituto de Assistencia Medica ao Servidor Publico Estadual IAMSPE","Debora Dourado Poli","巴西","Sao Paulo","Sao Paulo"],["Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP","Rogério Parra","巴西","Sao Paulo","Ribeirao Preto"],["Liga Norte Riograndense Contra O Cancer","Livia Celani","巴西","Rio Grande do Norte","Natal"],["Hepatogastro","Rodrigo Rocco","巴西","Sao Paulo","Sao Paulo"],["Complexo Hospitalar de Niteroi","Fernanda Nunes","巴西","Rio de Janeiro","Niterói"],["Faculdade de Medicina da Universidade Federal de Minas Gerais - Unidade de Pesquisa Clinica em Vacinas (UPqVac-UFMG)","Jorge Andrade Pinto","巴西","Minas Gerais","Belo Horizonte"],["Hospital Ernesto Dornelles","Cristina Flores","巴西","Rio Grande do Sul","Porto Alegre"],["Solare Trials","Marjorie Argollo","巴西","Sao Paulo","Sao Paulo"],["Centro de Pesquisa","Carlos Alexandre Antunes de Brito","巴西","Pernambuco","Recife"],["Acibadem City Clinic - Oncology Center","Asen Petrov","保加利亚","Sofia City Province","Sofia"],["University Multiprofile Hospital for Active Treatment - Tsaritsa Yoanna - ISUL, EAD","Plamen Penchev","保加利亚","Sofia City Province","Sofia"],["DCC Convex EOOD","Ludmila Tankova","保加利亚","Sofia City Province","Sofia"],["Acibadem City Clinic Tokuda Hospital","Petko Karagyozov","保加利亚","Sofia City Province","Sofia"],["UMHAT St. Ivan Rilski","Rosen Nikolov","保加利亚","Sofia City Province","Sofia"],["Multiprofile Hospital for Active Treatment 'Sveta Marina' EAD","Antonia Atanassova","保加利亚","Varna Province","Varna"],["MHAT Sv. Karidad EAD","Simon Sahak Sariyan","保加利亚","Plovdiv Province","Plovdiv"],["DCC NEOCLINIC EAD","Rayna Draganova","保加利亚","Sofia City Province","Sofia"],["Barrie GI Associates","Rima Petroniene","加拿大","Ontario","Barrie"],["Toronto Immune & Digestive Health Institute Inc.","Vivian Huang","加拿大","Ontario","Toronto"],["Gastroenterology and Internal Medicine Research Institute (GIRI)","Allen Whey Khye Lim","加拿大","Alberta","Edmonton"],["GIRI Gastrointestinal Research Institute","Astrid-Jane Williams","加拿大","British Columbia","Vancouver"],["University Of Manitoba Health Sciences Centre","Charles Bernstein","加拿大","Manitoba","Winnipeg"],["Viable Clinical Research","Bruce Musgrave","加拿大","Nova Scotia","Bridgewater"],["Covenant Health/Grey Nuns hospital","Shaalan Jesse Siffledeen","加拿大","Alberta","Edmonton"],["St. Joseph's Healthcare Hamilton","Neeraj Narula","加拿大","Ontario","Hamilton"],["Clinique IMD","Waqqas Afif","加拿大","Quebec","Montreal"],["CHUM - Hopital Notre-Dame","Robert Battat","加拿大","Quebec","Montréal"],["London Digestive Disease Institute","Vipul Jairath","加拿大","Ontario","London"],["ISCARE a.s.","Milan Lukas","捷克","Prague","Prague"],["Nemocnice Ceske Budejovice, a.s.","Martin Bortlik","捷克","Jihocesky kraj","Ceské Budějovice"],["Gastroenterologie, s.r.o., Hradec Kralove","Milan Siroky","捷克","Královéhradecky kraj","Hradec Kralova"],["Hepato-gastroenterologie HK, s.r.o.","Tomas Vanasek","捷克","Královéhradecky kraj","Hradec Králové"],["Oblastni nemocnice Kladno","Helena Hlavova","捷克","Stredocesky kraj","Kladno"],["IKEM","Pavel Drastich","捷克","Prague","Prague"],["Fakultni nemocnice Ostrava","Pavel Svoboda","捷克","Moravskoslezsky kraj","Ostrava"],["SurGal Clinic","Jan Ulbrych","捷克","Jihomoravsky kraj","Brno"],["Thomayerova nemocnice","Pavel Kohout","捷克","Prague","Prague"],["Hvidovre Hospital","Klaus Theede","丹麦","Capital Region of Denmark","copenhagen"],["Odense Universitetshospital","Jens Kjeldsen","丹麦","Region of Southern Denmark","Odense"],["Herlev Hospital","Jakob Benedict Seidelin","丹麦","N/A","Herlev"],["Nordsjaellands Hospital - Hillerod","Salvatore Leotta","丹麦","Region Hovedstaden","Hillerod"],["Centre hospitalier Lyon-Sud","Stephane Nancey","法国","Auvergne-Rhone-Alpes","Pierre-Bénite"],["CHU Rangueil","Cyrielle Gilletta de Saint Joseph","法国","Occitanie","Toulouse"],["CHU de Nice Hopital de l Archet","Adrien Nicolau","法国","Provence-Alpes-Cote-d’Azur","Nice"],["CHU Nancy Brabois","Benedicte Caron","法国","Grand-Est","Vandoeuvre-lès-Nancy"],["CHU Saint-Etienne - Hopital Nord","Xavier Roblin","法国","Auvergne-Rhone-Alpes","Saint-Priest-en-Jarez"],["Clinique Ambroise Pare","Yoram Bouhnik","法国","Ile-de-France","Neuilly-sur-Seine"],["CHU de Montpellier, Hopital Saint-Eloi","Romain Altwegg","法国","Occitanie","Montpellier"],["Hopital Henri Mondor","Mathieu Uzzan","法国","Ile-de-France","Créteil"],["Hopital Claude Huriez","Maria Nachury","法国","Hauts-de-France","Lille"],["CHU Amiens Picardie","Mathurin Fumery","法国","Hauts-de-France","Amiens"],["CHU de Nantes - L'Hotel-Dieu","Arnaud Bourreille","法国","Pays-de-la-Loire","Nantes"],["CHU de Bordeaux - Hospital Haut-Leveque","Pauline Riviere","法国","Nouvelle-Aquitaine","Pessac"],["Hopital Beaujon","Thomas Bazin","法国","Ile-de-France","Clichy"],["Hopital Robert Debré","Guillaume Cadiot","法国","Grand-Est","Reims"],["CHRU Besancon Hopital Jean Minjoz","Lucine Vuitton","法国","Bourgogne-Franche-Comté","Besancon"],["Hopital Bicêtre - Aphp Hopitaux Universitaires Paris-Sud","Aurelien Amiot","法国","Ile-de-France","Le Kremlin-Bicêtre"],["Medizinische Hochschule Hannover","Ursula Seidler","德国","Lower Saxony","Hannover"],["BSF Studiengesellschaft","Lars Fechner","德国","Saxony-Anhalt","Halle (Saale)"],["Universitatsklinikum Ulm","Jochen Klaus","德国","Baden-Württemberg","Ulm"],["Eugastro GmbH","Ingolf Schiefke","德国","Saxony","Leipzig"],["Universitaetsklinik Erlangen","Raja Atreya","德国","Bavaria","Erlangen"],["Medizinisches Versorgungszentrum (MVZ) Dachau","Wilfred Landry","德国","Bavaria","Dachau"],["Krankenhaus Waldfriede Mitte","Carsten Buening","德国","Berlin","Berlin"],["Universitaetsklinikum Mannheim","Wolfgang Reindl","德国","Baden-Württemberg","Mannheim"],["Universitatsklinikum Carl Gustav Carus Dresden","Renate Schmelz","德国","Saxony","Dresden"],["Universitaetsklinikum Halle (Saale)","Jens Walldorf","德国","Saxony-Anhalt","Halle (Saale)"],["Facharztpraxis für Gastroenterologie Karlshorst","Thomas Brunk","德国","Berlin","Berlin"],["Universitaetsmedizin Rostock","Johannes Reiner","德国","Mecklenburg-Vorpommern","Rostock"],["Universitatsklinikum Schleswig Holstein Kiel","Stefan Schreiber","德国","Schleswig-Holstein","Kiel"],["Universitatsklinikum Frankfurt","Irina Blumenstein","德国","Hesse","Frankfurt"],["Gastroenterologie Opernstrasse","Thomas Krause","德国","Hesse","Kassel"],["MVZ Gastroenterologie am Bayerischen Platz","Stefan Schubert","德国","Berlin","Berlin"],["Universitatsklinikum Jena","Andreas Stallmach","德国","Thuringia","Jena"],["Charite Universitatsmedizin Berlin - Campus Benjamin Franklin","Britta Siegmund","德国","Berlin","Berlin"],["Universitaetsklinikum Regensburg","Arne Kandulski","德国","Bavaria","Regensburg"],["Klinikum Fulda","Carsten Schmidt","德国","Hesse","Fulda"],["Klinikum der LMU Universitate Munchen","Benjamin Misselwitz","德国","Bavaria","Munich"],["Klinikum rechts der Isar an der Technischen Universitat Munchen","Matthias Treiber","德国","Bavaria","Munich"],["Sotiria General State Hospital of Chest Diseases","George Bamias","希腊","Attica","Athens"],["University Hospital of Heraklion","Ioannis Koutroubakis","希腊","Crete","Voutes"],["EVANGELISMOS GENERAL HOSPITAL OF ATHENS","Nikolaos Viazis","希腊","Attica","Athens"],["University General Hospital of Ioannina","Konstantinos Katsanos","希腊","Epirus","Ioánnina"],["Tzanio General Hospital of Piraeus","Spyridon Vrakas","希腊","Attica","Piraeus"],["General Hospital Of Athens Korgialenio Benakio H.R.C.","Georgios Tribonias","希腊","N/A","Athens"],["Semmelweis Egyetem","Emese Mihaly","匈牙利","Pest","Budapest"],["Semmelweis Egyetem","Pal Miheller","匈牙利","Pest","Budapest"],["Semmelweis Egyetem","Akos Ilias","匈牙利","Pest","Budapest"],["Pannónia Magánorvosi Centrum Kft","Robert Schnabel","匈牙利","Budapest","Budapest"],["Szegedi Tudomanyegyetem","Tamas Molnar","匈牙利","Csongrád","Szeged"],["Obudai Egeszsegugyi Centrum Kft","Robert Sike","匈牙利","Budapest","Budapest"],["Surat Institute of Digestive Sciences Hospitals","Rajiv Mehta","印度","Gujarat","Surat"],["Asian Institute Of Gastroenterology","Rupa Banerjee","印度","Telangana","Hyderabad"],["S. R. Kalla Memorial General Hospital","Mukesh Kalla","印度","Rajasthan","Jaipur"],["Sir Ganga Ram Hospital","Naresh Bansal","印度","Delhi","New Delhi"],["All India Institute of Medical Sciences","Vineet Ahuja","印度","Delhi","New Delhi"],["Gujarat Gastro and Vascular Hospital","Saumin Shah","印度","Gujarat","Surat"],["G.B. Pant Hospital","Ashok Dalal","印度","Delhi","New Delhi"],["P.D. Hinduja National Hospital and - Medical Research Center","Devendra Desai","印度","Maharashtra","Mumbai"],["Yashoda Super Speciality Hospitals","Ravi Bagepally","印度","Telangana","Secunderabad"],["Lisie Hospital","Mathew Philip","印度","Kerala","Kochi"],["Sushruta hospital and research centre","Laxmikant Desai","印度","Karnataka","Hubballi"],["Sheba Medical Center","Asaf Levartovsky","以色列","Tel Aviv","Ramat Gan"],["Shaare Zedek Medical Center","Benjamin Koslowsky","以色列","Jerusalem","Jerusalem"],["Tel Aviv Sourasky Medical Center","Nathaniel Cohen","以色列","Tel Aviv","Tel Aviv"],["Galilee Medical Center","Sbeit Wisam","以色列","Northern","Nahariyya"],["Bnai Zion Medical Center","Tova Rainis","以色列","Haifa","Kiryat Tiv'on"],["Rambam Medical Center","Roni Weisshof","以色列","Haifa","Haifa"],["Rabin Medical Center","Irit Avni-Biron","以色列","Tel Aviv","Kiryat Ono"],["Meir Medical Center","Michal Openhaim","以色列","Central","Kfar Saba"],["Wolfson Medical Center","Eran Israeli","以色列","Tel Aviv","Holon"],["Assuta MC","Adi Lahat-Zok","以色列","Southern","Ashdod"],["Policlinico Universitario Agostino Gemelli","Antonio Gasbarrini","意大利","Lazio","Rome"],["Istituto Clinico Humanitas","Alessandro Armuzzi","意大利","Lombardy","Rozzano"],["Ospedale San Raffaele","Silvio Danese","意大利","Lombardy","Milan"],["Ospedale Classificato Equiparato Sacro Cuore Don Calabria di Negrar","Angela Variola","意大利","Veneto","Negrar"],["Azienda Ospedaliera San Camillo - Roma","Rita Monterubbianesi","意大利","Lazio","Rome"],["Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico","Flavio Caprioli","意大利","Lombardy","Milan"],["Ospedale Isola Tiberina Gemelli Isola","Daniela Pugliese","意大利","Lazio","Roma"],["The Hospital of Hyogo College of Medicine","Shinichiro Shinzaki","日本","Hyōgo Prefecture","Nishinomiya"],["Tsujinaka Hospital Kashiwanoha","Ken Takeuchi","日本","Chiba Prefecture","Kashiwa"],["Tokyo Metropolitan Bokutoh Hospital","Yohei Furumoto","日本","Tokyo","Sumida"],["Kagoshima IBD Gastroenterology Clinic","Yohei Ono","日本","Kagoshima Prefecture","Kagoshima"],["Kyorin University Hospital","Tadakazu Hisamatsu","日本","Tokyo","Mitaka"],["Oita Red Cross Hospital","Tetsuya Ueo","日本","ōita Prefecture","ōita"],["Yokohama City University Medical Center","Reiko Kunisaki","日本","Kanagawa Prefecture","Yokohama"],["National Hospital Organization Mito Medical Center","Hiroyasu Ishida","日本","Ibaraki Prefecture","Ibaraki"],["Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital","Satoshi Motoya","日本","Hokkaidō Prefecture","Sapporo"],["Hamamatsu University Hospital","Ken Sugimoto","日本","Shizuoka Prefecture","Hamamatsu"],["Sapporo Higashi Tokushukai Hospital","Atsuo Maemoto","日本","Hokkaidō Prefecture","Sapporo"],["Yamanashi Prefectural Central Hospital","Yuichiro Kojima","日本","Yamanashi Prefecture","Kōfu"],["The Jikei University Hospital","Masayuki Saruta","日本","Tokyo","Tokyo"],["National Hospital Organization Osaka National Hospital","Yuko Sakakibara","日本","ōsaka Prefecture","Osaka"],["Center Hospital of the National Center for Global Health and Medicine","Junichi Akiyama","日本","Tokyo","Tokyo"],["Kitasato University Kitasato Institute Hospital","Shintaro Sagami","日本","Tokyo","Tokyo"],["Institute of Science Tokyo Hospital","Ryuichi Okamoto","日本","Tokyo","Tokyo"],["Matsuda Hospital","Masaki Yamashita","日本","Shizuoka Prefecture","Hamamatsu"],["Kumamoto University Hospital","Yoki Furuta","日本","Kumamoto Prefecture","Kumamoto"],["Saga University Hospital","Nanae Tsuruoka","日本","Saga Prefecture","Saga"],["Osaka Metropolitan University Hospital","Shuhei Hosomi","日本","ōsaka Prefecture","Osaka"],["Sapporo Medical University Hospital","Hiroshi Nakase","日本","Hokkaidō Prefecture","Sapporo"],["Aichi Medical University Hospital","Masanao Nakamura","日本","Aichi Prefecture","Nagakute"],["National Hospital Organization Shizuoka Medical Center","Yoshifumi Onishi","日本","Shizuoka","Shimizu"],["Takano Hospital","Shota Takano","日本","Kumamoto Prefecture","Kumamoto"],["University Malaya Medical Centre","Ida Normiha Hilmi","马来西亚","Kuala Lumpur","Kuala Lumpur"],["Hospital Serdang","Rosaida Hj. Md. Said","马来西亚","Selangor","Kajang"],["Hospital Ampang","Wan Ibrahim Nik Razima","马来西亚","Selangor","Ampang"],["Hospital Kuala Lumpur","Mohd Fairul Limun","马来西亚","Kuala Lumpur","Kuala Lumpur"],["Hospital Sultanah Nur Zahirah","Ahmad Syahidan Yusoff","马来西亚","Terengganu","Kuala Terengganu"],["Centro de Investigación Clínica Acelerada, SC","Emilio Bermudez Villegas","墨西哥","Ciudad de México","Mexico City"],["ONCARE","Manuel Martinez","墨西哥","Nuevo León","San Pedro Garza García"],["Centro de Alta Especialidad en Reumatologia e Investigacion","Jose Luis Vega Fonseca","墨西哥","San Luis Potosí","San Luis Potosí"],["Hospital General de Mexico","Jorge Luis de Leon Rendon","墨西哥","Ciudad de México","Mexico City"],["CIMOVA, Morals Vargas Centro de Investigación SC","Graciela Lopez Mata","墨西哥","Guanajuato","León"],["Roberto Ulises Cruz Neri","Roberto Cruz Neri","墨西哥","Jalisco","Tlajomulco de Zuniga"],["Keystone Clinical Trials","Karina Olvera Obregon","墨西哥","Ciudad de Mexico","Ciudad de Mexico"],["Academisch Medisch Centrum Universiteit van Amsterdam","Mark Lowenberg","荷兰","Noord-Holland","AMSTERDAM"],["UMC Utrecht","Herma Fidder","荷兰","UT","Utrecht"],["Erasmus MC","Annemarie de Vries","荷兰","ZH","Rotterdam"],["Elisabeth-TweeSteden Ziekenhuis","Robert Laheij","荷兰","North Brabant","Tilburg"],["Radboudumc","Marjolijn Duijvestein","荷兰","Gelderland","Nijmegen"],["Akershus Universitetssykehus","Stephan Brackmann","挪威","Viken","Lorenskog"],["Alesund sjukehus","Dag Arne Lihaug Hoff","挪威","More og Romsdal","Alesund"],["St. Olavs Hospital","Ann Elisabeth Ostvik","挪威","Trondelag","Trondheim"],["Universitetssykehuset Nord-Norge HF","Rasmus Goll","挪威","Troms og Finnmark","Tromso"],["Sykehuset Immlandet HF Gjovik","Oistein Hovde","挪威","Innlandet","Gjovik"],["Sykehuset Ostfold HF Kalnes","Henrik Wahlberg","挪威","Viken","Gralum"],["ETG Zamosc","Katarzyna Wojcik","波兰","Lublin Voivodeship","Zamosc"],["Centrum Medyczne Plejady","Monika Augustyn","波兰","Lesser Poland Voivodeship","Kraków"],["Centrum Medyczne Promed","Danuta Owczarek","波兰","Lesser Poland Voivodeship","Kraków"],["Centrum Medyczne Medyk","Rafal Filip","波兰","Podkarpackie Voivodeship","Rzeszów"],["REUMED Zespol Poradni Specjalistycznych Filia nr 2","Wit Danilkiewicz","波兰","Lublin Voivodeship","Lublin"],["Twoja Przychodnia - Szczecinskie Centrum Medyczne","Beata Gawdis-Wojnarska","波兰","West Pomeranian Voivodeship","Szczecin"],["WIP Warsaw IBD Point Profesor Kierkus","Jaroslaw Kierkus","波兰","Masovian Voivodeship","Warsaw"],["GASTROMED Sp. z o.o.","Adam Kopon","波兰","Kuyavian-Pomeranian Voivodeship","Toruń"],["EuroMediCare Szpital Specjalistyczny z Przychodnia","Patryk Smolinski","波兰","Lower Silesian Voivodeship","Wroclaw"],["Centrum Medyczne Medis ManerMed Sp Z O O","Maria Klopocka","波兰","N/A","Bydgoszcz"],["Centrum Medyczne Oporow","Radoslaw Kempinski","波兰","Lower Silesian Voivodeship","Wroclaw"],["Sonomed Sp. z o.o.","Anna Wiechowska-Kozlowska","波兰","West Pomeranian Voivodeship","Szczecin"],["Twoja Przychodnia","Agata Lukawska","波兰","Opole Voivodeship","Opole"],["H-T Centrum Medyczne Endoterapia","Tomasz Romanczyk","波兰","Silesian Voivodeship","Tychy"],["Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy","Edyta Zagorowicz","波兰","Masovian Voivodeship","Warsaw"],["Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie","Halina Cichoz-Lach","波兰","Lublin Voivodeship","Lublin"],["Medicus Zaniewski i Bilski","Anna Wos-Zaniewska","波兰","N/A","Olsztyn"],["Centro Hospitalar de Lisboa Norte Hospital Santa Maria","Samuel Fernandes","波兰","Lisbon","Lisbon"],["Hospital de Portimao-Centro Hospitalar do Barlavento Algarvio","Helena Sousa","葡萄牙","Faro","Portimao"],["Hospital de Braga","Bruno Arroja","葡萄牙","Braga","Braga"],["HOSP. DA LUZ LISBOA","Joana Reves","葡萄牙","Lisbon","Lisboa"],["Centro Hospitalar de Setubal","Claudio Martins","葡萄牙","Setubal","Setubal"],["Spitalul Clinic Colentina","Radu Bogdan Mateescu","罗马尼亚","Bucharest","Bucharest"],["Institutul Clinic Fundeni","Carmen Monica Preda","罗马尼亚","Bucharest","Bucharest"],["Spitalul Clinic Judetean de Urgenta \","Catalina Mihai","罗马尼亚","Iasi County","Iasi"],["Gastro Med S R L","Andrada Seicean","罗马尼亚","N/A","Cluj-Napoca"],["Oncohelp Medical Center","Razvan Gheorghe Diaconescu","罗马尼亚","TM","Timisoara"],["Baneasa Tumor Center Hospital","Eugeniu Craciun","罗马尼亚","Bucuresti","Bucuresti"],["Cliniq s.r.o.","Tibor Hlavaty","斯洛伐克","Bratislava Region","Bratislava"],["ENDOMED s.r.o","Miroslav Fedurco","斯洛伐克","Kosice Region","Kosice"],["FNsP F.D.R. Banska Bystrica","Jozef Balaz","斯洛伐克","Banská Bystrica Region","Banská Bystrica"],["KM Management spol. s r.o.","Milos Gregus","斯洛伐克","Nitra Region","Nitra"],["GASTRO I. s.r.o.","Bohus Bunganic","斯洛伐克","Presov Region","Presov"],["GASTRO LM","Lubomir Mihalkanin","斯洛伐克","Presovsky kraj","Presov"],["UVN SNP Ruzomberok - FN","Marek Gembala","斯洛伐克","Zilina Region","Ruzomberok"],["Samsung Medical Center","YoungHo Kim","韩国","Seoul","Seoul"],["Inje University Haeundae Paik Hospital","Taeoh Kim","韩国","South Gyeongsang Province","Busan"],["Kyung Hee University Hospital","Changkyun Lee","韩国","Seoul","Seoul"],["Asan Medical Center","ByongDuk Ye","韩国","Seoul","Seoul"],["Seoul National University Hospital","Seongjoon Koh","韩国","Seoul","Seoul"],["Korea University Ansan Hospital","Ja Seol Koo","韩国","Gyeonggi Province","Ansan"],["The Catholic Univ. of Korea, DaeJeon St. Mary’s Hospital","SangBum Kang","韩国","South Chungcheong Province","Seongnam"],["HOSP. VIRGEN MACARENA","Federico Arguelles Arias","西班牙","Sevilla","Sevilla"],["Alvaro Cunqueiro Hospital","Vicent Hernandez Ramirez","西班牙","Pontevedra","Vigo"],["HOSP. UNIV. MIGUEL SERVET","Raquel Vicente Lidon","西班牙","Zaragoza","Zaragoza"],["HOSP. UNIV. INFANTA LEONOR","Angel Ponferrada Diaz","西班牙","Madrid","Madrid"],["HOSP. CLINICO UNIV. DE SANTIAGO","Manuel Barreiro","西班牙","A Coruna","Santiago de Compostela"],["HOSP. GRAL. UNIV. DE ALICANTE","Ana Gutierrez Casbas","西班牙","Valencia","Alicante"],["Gastroenterologische Praxis Balsiger und Seibold","Pascal Juillerat","瑞士","Bern","Bern"],["Universitatsspital Zurich","Luc Biedermann","瑞士","Zürich","Zürich"],["Kantonsspital St.Gallen","Stephan Brand","瑞士","St. Gallen","St. Gallen"],["Ege Universitesi Tip Fakultesi","Nalan Unal","土耳其","Bornova","Izmir"],["Mersin University Medical Faculty","Engin Altintas","土耳其","Icel","Mersin"],["Istanbul University Cerrahpasa Medical Faculty","Aykut Ferhat Celik","土耳其","Turkey","Istanbul"],["Kocaeli University Medical Faculty","Hasan Yilmaz","土耳其","Kocaeli","Kocaeli"],["Antalya Training And Research Hospital","Ayhan Hilmi Cekin","土耳其","Antalya","Antalya"],["Sanko üniversitesi","Sezgin Barutcu","土耳其","Gaziantep","Gaziantep"],["Izmir Katip Celebi University Ataturk Training and Research Hospital","Zehra Betul Pakoz","土耳其","Karabaglar","Izmir"],["Bezmialem University Medical Faculty","Metin Basaranoglu","土耳其","Istanbul","Istanbul"],["Izmir Sehir Hastanesi","Gozde Dervis Hakim","土耳其","Izmir","Izmir"],["St George's Hospital","Kamal Patel","英国","England","Greater London"],["Addenbrookes Hospital","Tim Raine","英国","England","Cambridgeshire"],["Guy's and St Thomas' Hospital","Mark Samaan","英国","England","Greater London"],["Fairfield General Hospital","Jimmy Limdi","英国","England","Greater Manchester"],["Oxford University Hospitals NHS Foundation Trust","Oliver Brain","英国","England","Oxfordshire"],["Whipps Cross University Hospital","Sami Hoque","英国","England","Greater London"],["The Newcastle upon Tyne Hospitals NHS Foundation Trust - Royal Victoria Infirmary (RVI)","Ally Speight","英国","England","Tyne and Wear"],["Kings College Hospital","Polychronis Pavlidis","英国","England","London"],["Royal Devon and Exeter Hospital","Nicholas Kennedy","英国","England","Devon"],["Cardiff and Vale University Health Board - University Hospital of Wales","Dharmaraj Durai","英国","Wales","Cardiff"],["Russell's Hall Hospital","Shanika De Silva","英国","England","Dudley"],["Ninewells Hospital","Craig Mowat","英国","Scotland","Dundee City Council"],["Tyler Research Institute, LLC","Aaron Duvall","美国","Texas","Tyler"],["Weill Cornell Medical College","Ellen Scherl","美国","New York","New York City"],["University of North Carolina","Animesh Jain","美国","North Carolina","Chapel Hill"],["Virginia Mason Medical Center","Timothy Zisman","美国","Washington","Seattle"],["Peak Gastroenterology Associates","Bhaktasharan Patel","美国","Colorado","Colorado Springs"],["New York Gastroenterology Associates","Arthur Kornbluth","美国","New York","New York City"],["GCP Clinical Research","Alan G. Weintraub","美国","Florida","Tampa"],["Lenox Hill Hospital","Arun Swaminath","美国","New York","New York City"],["Tri-State Gastroenterology Assoc","Michael Jones","美国","Kentucky","Crestview Hills"],["Integris Health Baptist Medical Center","David Stokesberry","美国","Oklahoma","Oklahoma City"],["Northshore Gastroenterology Research, LLC","Mohamed Naem","美国","Ohio","Westlake"],["GI Alliance - Tacoma","William Holderman","美国","Washington","Tacoma"],["Great Lakes Gastroenterology Research, LLC","Keith Friedenberg","美国","Ohio","Mentor"],["GI Alliance - Southlake","Timothy Ritter","美国","Texas","Southlake"],["Southern Star Research Institute, LLC","Jeff Bullock","美国","Texas","San Antonio"],["University of Texas Southwestern Medical Center","Moheb Boktor","美国","Texas","Dallas"],["Endoscopic Research, INC","Henry Levine","美国","Florida","Orlando"],["Frontier Clinical Research","Marc Happe","美国","Pennsylvania","Smithfield"],["Florida Research Center Inc.","Manuel Rodriguez","美国","Florida","Bradenton"],["Medical Associates Research Group, Inc.","Hyun Sil Kim","美国","California","San Diego"],["University of California San Francisco","Sara Lewin","美国","California","San Francisco"],["University of Chicago","David Rubin","美国","Illinois","Chicago"],["Gastroenterology Clinic of Acadiana","Jacque Noel","美国","Louisiana","Lafayette"],["Detroit Clinical Research Center","Steven Katzman","美国","Michigan","Farmington Hills"],["Woodholme Gastroenterology Associates","Kenolisa Onwueme","美国","Maryland","Glen Burnie"],["Sanchez Clinical Research, Inc","Mirel Sanchez","美国","Florida","Miami"],["Providence Portland Medical Center","Phillip Kiyasu","美国","Oregon","Portland"],["UC Davis Medical Center","Eric Mao","美国","California","Sacramento"],["Mayo Clinic","Edward Loftus","美国","Minnesota","Rochester"],["Swedish Medical Center","Jason Harper","美国","Washington","Seattle"],["Dartmouth-Hitchcock Medical Center","Corey Siegel","美国","New Hampshire","Grafton County"],["DHAT Research Institute","Harry Sarles","美国","Texas","Garland"],["Atlanta Gastroenterology Specialists","Thalvinder Sangha","美国","Georgia","Suwanee"],["NYU Langone Medical Center","Jordan Axelrad","美国","New York","New York City"],["Cedars Sinai Medical Center","Andres Yarur","美国","California","West Hollywood"],["Clinnova Research","Amit Bhanvadia","美国","California","Orange"],["Mayo Clinic","Manreet Kaur","美国","Arizona","Scottsdale"],["Gastro SB Clinic","Erick Alayo","美国","California","Chula Vista"],["Delta Research Partners Monroe","Henry Hill Hinkle III","美国","Louisiana","Monroe"],["AZ Gastro Care","Shahbaz Qureshi","美国","Arizona","Mesa"],["United Gastroenterologists","Seyedehsan Navabi","美国","California","Los Alamitos"],["Palmetto Primary and Specialty Care Physicians, Charleston","Brett Van Leer-Greenberg","美国","South Carolina","Summerville"],["Hackensack Meridian Health - Hackensack University Medical Center","Alyssa Parian","美国","New Jersey","Hackensack"],["Virtua Health","Sanket Patel","美国","New Jersey","Marlton"],["NYP Brooklyn Methodist Gastroenterology and Hepatology Clinical Trials Team","Mike Mintz","美国","New York","Brooklyn"],["University of Maryland Digestive Health Center","Aline Charabaty","美国","Maryland","Baltimore"],["Mesa Medical Research - Austin","Masi Khaja","美国","Texas","Austin"],["Digestive Disease Medicine","Harvey Allen","美国","New York","Utica"]]

序号	机构名称	主要研究者	国家	省（州）	城市

[["中山大学附属第一医院临床药物、器械和医疗新技术伦理委员会","同意","2026-06-08"]]

序号	名称	审查结论	批准日期/备案日期

进行中（尚未招募）

目标入组人数	国内: 60 ； 国际: 644 ；
已入组人数	国内: 登记人暂未填写该信息； 国际: 1 ；
实际入组总人数	国内: 登记人暂未填写该信息； 国际: 登记人暂未填写该信息；

第一例受试者签署知情同意书日期	国内：登记人暂未填写该信息；     国际：2026-05-23；
第一例受试者入组日期	国内：登记人暂未填写该信息；     国际：2026-06-12；
试验完成日期	国内：登记人暂未填写该信息；     国际：登记人暂未填写该信息；